ABZOOM BIOLABS, Inc P.O. Box 726578 Dallas, TX, USA 469-458-7643 order@abzoom.com

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ABZOOM BIOLABS, Inc P.O. Box 726578 Dallas, TX, USA


Cell signalling pathways

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response. Proteins responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used.The changes elicited by ligand binding (or signal sensing) in a receptor give rise to a signaling cascade, which is a chain of biochemical events along a signaling pathway. When signaling pathways interact with one another they form networks, which allow cellular responses to be coordinated, often by combinatorial signaling events. At the molecular level, such responses include changes in the transcription or translation of genes, and post-translational and conformational changes in proteins, as well as changes in their location. These molecular events are the basic mechanisms controlling cell growth, proliferation, metabolismand many other processes.In multicellular organisms, signal transduction pathways have evolved to regulate cell communication in a wide variety of ways.